Explorer The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche
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The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche☆
Ischaemia leads to increased proliferation of progenitors in the subependymal zone (SEZ) neurogenic niche of the adult brain and to generation and migration of newborn neurons. Here we investigated the spatiotemporal characteristics of the mitotic activity of adult neural stem and progenitor cells in the SEZ during the sub-acute and chronic post-ischaemic phases. Ischaemia was induced by perfor...
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